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Newest Definitions
Evolving Terminologies for Emerging Technologies 

Comments? Suggestions Revisions? Mary Chitty  mchitty@healthtech.com
Last revised April 15, 2014.
* newest of the new


* assay validation:  Assays & Screening

Bayesian clinical trials: Clinical trials

* Bayesian statistics: Clinical Informatics

* bioelectronics: Biomaterials & bioengineering

biological chemistry: Chemistry

biomarker guidelines: Biomarkers 

biomathematics Algorithms

biomedical polymers: Biomaterials

biomolecular screening: Assays & screening

cell specific biomarkers: Biomarkers

cellular dielectric spectroscopy CDS: Technologies

chaperome: -Omes & -omics

* Chimeric Antigen Receptors CAR: Drug and disease targets  

* clinical bioinformatics: Clinical Informatics

* clinical informatics: Clinical Informatics

* clinical pharmacology: Pharmacogenomics  

Clinical Trial Design Task Force: Clinical Trials

combination therapies:  Drug Discovery & Development

* comparative effectiveness research: Research

comparative systems biology: Genomic Manipulation & Disruption

* compound quality: Chemistry

computational physiology: Drug discovery informatics

computational sensing: Labels Signaling & detection

connectome: -Omes & -omics

Copy Number Polymorphisms CNPs: SNPs and Genetic Variations

developability: Drug discovery & development 

diffusion tensor imaging: Molecular imaging

* digital PCR dPCR: PCR    

* diseasome: Molecular Medicine

disproportionate drug metabolite: Drug safety, Pharmacovigilance & toxicology

drug metabolism: Pharmacogenomics

* Dynamic Light Scattering DLS: Bioprocessing     

* electroceuticals: Biomaterials & bioengineering

eSNPs expression SNPs: SNPs and genetic variations

evidence based toxicology: Drug safety, Pharmacovigilance & toxicology

exploratory IND:  Regulatory Affairs

expressomics: -Omes & -omics

follow-on drug: Drug discovery & development 

fragment based drug discovery  Assays and screening

genetic susceptibility: Molecular diagnostics -- genetic & genomic testing

GIS Geographic Information Systems: Molecular Medicine

glycomimetics: Glycosciences

green chemistry: Chemistry

GWAS Genome Wide Association Sequencing: Genomic informatics

* health disparities: Molecular Medicine

human induced pluripotent stem cells hiPS: Stem cells

inflammasome: -Omes & -omics

integrative and organ systems pharmacology: Pharmacogenomics

* in vitro adventitious assays: Assays & screening   

in vitro diagnostic multivariate index assays IVDMIAs: Genetic & genomic testing

integrative biology: Pharmaceutical biology

kidney safety biomarkers: Biomarkers

label free detection: Labels Signaling & detection

lead hopping: Assays

* lipidomics: 'Omes & 'omics 

* macrocycles: Chemistry

materials chemistry: Chemistry

*meaningful use Clinical Informatics

medical resequencing: Sequencing

mesoscopic biology: Expression genes & proteins

metabolite: Drug safety, Pharmacovigilance & toxicology

microdosing Pharmacogenomics

microtissues: Cell biology

mitochondriomics: -Omes & -omics

molecular biosensors: Labels Signaling & detection

molecular crowding: Biomolecules

molecular electronics: Nanoscience & miniaturization

molecular events: Cancer diagnostics, genomics, prognostics & therapeutics 

* molecular pathology: Molecular diagnostics    

molecular pharmacology Pharmacogenomics

mRNA biomarkers: Biomarkers

nanolabels: Labels Signaling & detection

nanomedicine: Nanoscience & miniaturization 

nanotechnology in the clinical laboratory setting: Molecular Medicine

natural competence: DNA

network pharmacology: Pharmacogenomics

next generation sequencing: Sequencing

niche busters: Drug discovery & development

-Omes & -omics: Lots of new terms including alleome, chromatinomics, chromosonics, cryobionomics, embryogenomics, epitomics, fragonomics, lectinomics, mitogenomics, Nobonomics, paleogenomics, RNome, RNomics, separomics, strainomics, transgenomics

oncolytic: Cancer diagnostics, prognostics & therapeutics

* openFDA: Regulatory

* optical mapping: Sequencing

* optogenetics:  Genomics  

* patent cliff: Legal & intellectual property   

* patent trolls  Legal and intellectual property    

* pathology informatics: Clinical Informatics

patient engagement: Molecular Medicine

patient navigation:  Cancer diagnostics, genomics, prognostics & therapeutics

pharmacokinetics: Pharmacogenomics

* Personal Health Record: Clinical Informatics

pharmacological biomarkers: Biomarkers

pharmacologically active metabolite: Drug safety, Pharmacovigilance & toxicology

Phase II clinical trial design: Clinical Trials

Phase zero, Phase O: Regulatory

physiologically based pharmacodynamics: Pharmacogenomics

pipeline problem:  Drug discovery

post-genomic chemistry: Chemistry

preclinical safety biomarkers: Biomarkers

predictive ADME: Drug safety & pharmacovigilance

predictive biomarkers: Biomarkers

predictive toxicology: Drug safety, toxicology & pharmacovigilance

process chemistry: Chemistry

Proteomic Standards Initiative: Proteomics

* psychiatome: -Omes & -omics

* public health informatics Clinical Informatics

quantitative pharmacology: Pharmacogenomics

* quantitative systems pharmacology: Pharmacogenomics  

* real world data: Clinical Informatics

* REMS Risk
Evaluation and Mitigation Strategy : Drug Safety

resourceome: -Omes & -Omics   

ridiculome: -Omes & -Omics

safety pharmacology: Drug Safety & Pharmacovigilance

scaffold hopping: Chemistry

selection biomarkers: Biomarkers

semantic systems biology: Bioinformatics

Sentinel Initiative: Drug safety, toxicology & pharmacovigilance

seromics:  See under autoantibodies: Cancer diagnostics & genomics

small molecule biomarkers: Biomarkers

soft drug design: Molecular modeling

solubility: Chemistry

* strategic investors: Financial & pharmacoeconomics

* structural variants: SNPs & genetic variants

supramolecular electronics: Nanoscience & miniaturization

* synthetic biology: Drug discovery informatics

* systems chemical biology: Medicinal & Pharmaceutical Chemistry  

systems pharmacology: Pharmacogenomics

target hopping: Drug targets

therapeutic antibodies: Drug targets

top-down mass spectrometry: Mass spectrometry

* translational bioinformatics: Clinical Informatics

translational biomarkers: Biomarkers

translational pharmacodynamics: Pharmacogenomics

* tumor microenvironment (TME):  Cancer      

type 0, type I, type II biomarkers: Biomarkers

* venture philanthropy: Financial & pharmacoeconomics

women's health: Molecular Medicine

women's health statistical modeling: Molecular Medicine

Bibliography
Alpha glossary index
How to look for other unfamiliar  terms

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