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Newer Definitions
Evolving Terminologies for Emerging Technologies 

Comments? Suggestions Revisions?
Mary Chitty MSLS  mchitty@healthtech.com
Last revised January 10, 2020.

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Assays & Screening
assay validation
biomolecular screening
fragment-based drug discovery
in vitro adventitious assays
lead hopping

Best practices, lessons learned, ongoing challenges
fail fast

Bioinformatics
comparative systems biology
semantic systems biology

Biologics
therapeutic antibodies

Biomarkers 
biomarker guidelines
cell specific biomarkers
kidney safety biomarkers
mRNA biomarkers
pharmacological biomarkers
preclinical safety biomarkers
predictive biomarkers
selection biomarkers
small molecule biomarkers
translational biomarkers
type 0, type I, type II biomarkers

Biomaterials & Medical Devices
bioelectronics
electroceuticals
polymers, biomedical


Biomolecules
molecular crowding

Bioprocessing 
Dynamic Light Scattering DLS

Business
startups
startups philanthropic

Cancer & immuno-oncology
immuno-oncology IO
imprecision medicine
oncolytic virotherapy
oncosomes
patient navigation
seromics: See under autoantibodies
Tumor Tumor MicroEnvironment TME

Cell & Tissue technologies
diffusion tensor imaging
microtissues
synthetic biology
tumoroid

Chemistry
biological chemistry
compound quality
green chemistry
macrocycles
materials chemistry
post-genomic chemistry
process chemistry
scaffold hopping
solubility
systems chemical biology
tool compounds

Clinical& Medical informatics
Bayesian clinical trials
Bayesian statistics
biomathematics
clinical bioinformatics
clinical informatics
comparative effectiveness research
meaningful use
pathology informatics
patient engagement
personal health record
population health
public health informatics
Real World Data RWD
translational bioinformatics

Clinical Trials
basket trials
Clinical Trial Design Task Force
Phase II clinical trial design

Data Science & Machine Learning
artificial general intelligence
artificial narrow intelligence
augmented intelligence
data lake
data scientist
data stewardship
data swamp
deep learning
FAIR: Findable Accessible Interoperable
Reproducible

interoperability
machine intelligence
machine learning

predictive analytics

DNA
natural competence

Drug & disease targets
Chimeric Antigen Receptors CAR 
target hopping

Drug Discovery & Development
combination therapies
developability
follow-on drug
microdosing
niche busters
pipeline problem

Drug Discovery informatics
computational physiology
integrative biology
soft drug design

Drug safety, Pharmacovigilance & toxicology
disproportionate drug metabolite
evidence-based toxicology
metabolite
pharmacologically active metabolite
predictive ADME
predictive toxicology
REMS Risk Evaluation and Mitigation Strategy
safety pharmacology
Sentinel Initiative

Expression genes & proteins
mesoscopic biology

Financial
cross over funding
strategic investors
valley of death
venture philanthropy

Gene definitions      
genes human number of

Genomic informatics
GWAS Genome Wide Association Sequencing

Genomic technologies
prime editing

Genomics  
optogenetics

Glycosciences
glycomimetics

Labels Signaling & detection
computational sensing
label free detection
molecular biosensors
nanolabels

Legal & intellectual property   
patent cliff
patent trolls

Mass spectrometry
top-down mass spectrometry 

Molecular Diagnostics -- genetic & genomic testing
genetic susceptibility
in vitro diagnostic multivariate index assays IVDMIAs
liquid biopsy
molecular pathology
nanotechnology clinical labor setting

Molecular Imaging
light-sheet fluorescence microscopy

Molecular Medicine
diseasome
GIS Geographic Information Systems
health disparities
nanomedicine
precision medicine

Nanoscience & miniaturization
molecular electronics
supramolecular electronics

-Omes & -omics
chaperome
connectome
expressomics
inflammasome
lipidomics
microbiome
mitochondriomics
psychiatome
resourceome
ridiculome

Other new terms include alleome, chromatinomics, chromosonics, cryobionomics, embryogenomics,
epitomics, fragonomics, lectinomics, mitogenomics, Nobonomics, paleogenomics, RNome, RNomics, separomics, strainomics, transgenomics



Ontologies & Taxonomies
knowledge graph
ontology alignment
ontology mapping
reproducibility

PCR    
Agglutination-PCR (ADAP)
digital PCR dPCR
immuno-PCR

Pharmacogenomics  
clinical pharmacology 
drug metabolism
integrative and organ systems pharmacology
molecular pharmacology
network pharmacology
pharmacokinetics
physiologically based pharmacodynamics
quantitative pharmacology
quantitative systems pharmacology
systems pharmacology
translational pharmacodynamics

Protein informatics
Proteomic Standards Initiative

Protein  Technologies
directed evolution

Regulatory
exploratory IND
OpenFDA
Phase zero, Phase O

Research
interdisciplinary research
truth
uncertainty

Sequencing
Next Generation Sequencing NGS
optical mapping

SNPs and Genetic Variations
Copy Number Polymorphisms CNPs
eSNPs expression SNPs
structural variants

Stem cells
human induced pluripotent stem cells hiPS

Technologies
Cellular Dielectric Spectroscopy CDS

 

Bibliography

How to look for other unfamiliar  terms

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